GASTROINTESTINAL (GI) SYMPTOMS
- Abdominal pain
AIP is a rare inherited disease that can cause serious symptoms that affect your body, such as your brain and nervous system. The most common symptom is severe abdominal pain. There is no cure for AIP, but it can be managed.
The most common symptom of AIP is severe abdominal pain that usually cannot be relieved with pain medicine such as Advil® (ibuprofen) or Tylenol® (acetaminophen). More than 85% of people who develop AIP symptoms have abdominal pain.
AIP attacks can be very serious. And symptoms may get worse over time. Untreated attacks can cause serious damage to your nervous system —including paralysis, and even death. That's why early diagnosis and treatment of AIP (acute intermittent porphyria) is so important.
If you have any of the symptoms listed above, talk to your doctor right away.
AIP is caused by a partial lack of an enzyme known as porphobilinogen deaminase (PBGD). An enzyme is a type of protein that helps to regulate the body’s tissues and organs. Enzymes carry out almost all of the thousands of chemical reactions that take place in cells. PBGD is an enzyme that is used in the production of heme, a molecule that carries oxygen throughout your body.
If you have AIP, you have about half of the normal amount of PBGD enzyme activity in your body. This is usually enough for your body to do what it is supposed to do. But triggers like those listed above can upset your body’s chemical balance and prompt your body to produce more heme. Reduced PBGD enzyme activity can cause heme production to get backed up partway through the process. This can lead to the production and build-up of certain molecules that can be harmful to the body and, in turn, lead to symptoms of AIP.About PANHEMATIN Learn how PANHEMATIN treats AIP COULD IT BE AIP? Download a symptoms checklist COULD IT BE AIP? Download a symptoms checklist
PANHEMATIN® is a hemin for injection prescription medication used to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women, after initial carbohydrate therapy is known or suspected to be inadequate.
Limitations of Use
Indications And UsagePANHEMATIN is a hemin for injection prescription medication used to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women, after initial carbohydrate therapy is known or suspected to be inadequate.
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