Important Safety Information
Prescribing Information
Indications and Usage
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Indications And Usage

PANHEMATIN® is a hemin for injection prescription medication used to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women, after initial carbohydrate therapy is known or suspected to be inadequate.

Limitations of Use

  • Before giving PANHEMATIN, consider an appropriate trial of carbohydrates [i.e., 400 grams of glucose (a carbohydrate or sugar) per day for 1 to 2 days].
  • Attacks of porphyria may progress to a point where irreversible nerve damage has occurred. PANHEMATIN therapy is intended to prevent an attack from reaching the critical stage of nerve breakdown. PANHEMATIN is not effective in repairing nerve damage that has already occurred.

Indications and Important
Safety Information

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Indications And Usage

PANHEMATIN is a hemin for injection prescription medication used to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women, after initial carbohydrate therapy is known or suspected to be inadequate.

Important Safety Information

  • PANHEMATIN is not for patients known to be allergic to this drug.
  • Vein inflammation is possible. Use a large arm vein or a central line to administer PANHEMATIN to minimize the possibility of vein inflammation.
  • Elevated iron levels may occur. Your doctor must monitor your iron levels if you receive multiple courses of PANHEMATIN.
  • PANHEMATIN has a passing and mild blood thinning effect. Avoid blood thinners during PANHEMATIN therapy.
  • Reversible kidney shutdown has occurred when too high a dose of PANHEMATIN was given in a single dose.
  • PANHEMATIN may carry a risk of transmitting agents that can cause infections, such as viruses, and theoretically, the Creutzfeldt-Jakob disease (CJD) agent.
  • Most common side effects are headache, fever, infusion site reactions, and vein inflammation.
  • To report SUSPECTED SIDE EFFECTS, contact Recordati Rare Diseases Inc. at 1-888-575-8344, or FDA at 1800-FDA-1088 or www.fda.gov/medwatch.
  • When taking PANHEMATIN, do not take drugs such as estrogens (e.g., oral contraceptives), barbiturates (drugs that help with sleep and used to treat epilepsy) or steroids (body hormone-like drugs), because such drugs can trigger an attack or make an attack worse.
For more information, please see PANHEMATIN Full Prescribing Information at www.recordatirarediseases.com.

Important Safety Information

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